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1995年创刊，中华人民共和国卫生部主管，中华医学会、国际医药卫生导报社主办。本刊是综合性医学学术期刊，主要栏目：科研课题、基础研究、专家述评、临床研究、病例报告、药物与临床、药学研究、临床检验、中医中药、预防医学、护理研究、医学动态等。
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首页>国际医药卫生导报杂志
- 杂志名称：国际医药卫生导报杂志
- 主管单位：中华人民共和国卫生和计划生育委员会
- 主办单位：中华医学会;国际医药卫生导报社
- 国际刊号：1007-1245
- 国内刊号：44-1417/R
- 出版周期：半月刊
期刊荣誉：中国期刊全文数据库(CJFD)期刊收录：国家图书馆馆藏, 上海图书馆馆藏, 知网收录(中), 维普收录(中), 万方收录(中)
Relationship between the mutation of G239V point in SLC17A3 gene and primary gout
WANG Bao-ping；LI Chang-gui；HAN Lin；JIA Zhao-tong
关键词：Gout, SLC17A3, single nucleotide polymorphism, Taq man probe, Real-time fluorescence quantitative PCR
摘要：Objective To explore the relationship between the mutation of G239V point in SLC 17A3 gene and primary gout.Methods The single nucleotide polymorphism (SNP) of gene in 530 sporadic patients with primary gout was detected with Taq man probe real-time fluorescence quantitative PCR.Results No mutation was detected the site of G239V in SLC17A3 gene in the 530 patients.Conclusions Attack of primary gout doesn' t correlate with the mutation of G239V point in SLC17A3 gene,indicating heterogeneity of primay gout.
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